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You can see all the photos from the 5% Day at Whole Foods event, at our Facebook page, some are here:
To purchase, go to our store to pay with Paypal. Singing in English and Spanish Javier is a gifted singer song writer Audio clip: Adobe Flash Player (version 9 or above) is required to play this audio clip. Download the latest version here. You also need to have JavaScript enabled in your browser. World renowned face and body painter Lynne Jamieson created a work of art to prepare Lily for the upcoming 2012 Lily’s Well-NESS Calendar. It is so wonderful when Lily participates in age appropriate activites that she enjoys. This is the first time getting her face painted. Thank you Lynne for graciously donating your time. Scientists find a completely new function for a known protein family The cortex is comprised of several billion nerve cells. These cells process movement and sensory information and govern speech and logical thinking. An international team led by scientists of the Max Planck Institute of Neurobiology in Martinsried was able to reveal an important mechanism for the development of this complex brain structure. The protein family known as FLRTs are located on the surface of young nerve cells, from where they regulate embryonic tissue cohesion – for example in the heart’s development. The scientists were able to show in mice that FLRT proteins have a second, so far unknown function: part of the protein can split off and bind as a ligand to the receptors of another nerve cell. This interaction leads to the repulsion of young, roaming nerve cells and helps to guide them through the cortex – an important insight into the general development of the cortex. (EMBO Journal, online publication 14. June 2011) Masterminds like Mozart, Einstein or van Gogh owe their exceptional talents to their cortex. The nerve cells in this area also allow normal people like us to learn, speak, process sensory information and to think logically. For these activities to work at their best, it is essential that the nerve cells connect with their correct partner cells. This is no easy task, since the developing cortex is a site of intense activity: thousands of young nerve cells migrate into this area, where they either proceed directly to their target location or wait for some time before they continue on their way. Bit by bit, the typical cortex structure, consisting of layers of cell bodies, develops. Once the nerve cells have reached their destination, they extend long processes, so-called neurites into the surrounding area. They connect in part to neighboring cells and in part to cells in other cortex layers. However, in this turmoil of billions of wandering nerve cells and growing neurites, how does a cell know where to go and in which direction to send its neurites?
Proteins as growth pilots The researchers were able to show that part of the FLRT receptor is able to split off. The thus mobile protein part can then bind to Unc5 receptors on other nerve cells. The result of this interaction was impressive: the growth cone of the filament collapsed, the filament retracted and stopped, or continued its growth in another direction. In addition to the already known attractive function of FLRT proteins, the split-off part of the protein can apparently act as a repulsive signal for nerve cells. “It is rather unusual and therefore came as a surprise that a receptor, or part of it, becomes a ligand for another receptor”, explains Rüdiger Klein, the project’s head. “It seems that the more complex an organism gets, the more tasks its individual components need to carry out.” Guidance system in the cortex Arturo Tenacio says: Congratulations to this international team on this fascinating finding. Hopefully it will serve to advance in the discovery of restoring guidance and, therefore function and health, for the nerve cells that, for some reason, were not able to reach their destination during the pregnancy period. Lily is a real sweetheart. I always look forward to seeing her and I am happy to see her. She has a cheerful smile. I enjoy reading with her, we watch baseball together sometimes. I love holding her on my lap and reading to her. I especially love her smile. I know she has a full therapy schedule and wonderful people work with her together with her parents. by Roy Haenel Roy is a volunteer and dear family friend. He visits with Lily and our family every week. He has done so for the past 6 years. Roy is a faithful supporter of Lily’s Well-NESS. We give thanks for you Roy! Lily spent over a week at IAHP receiving an intensive treatment. She is showing great improvement in the mobility of her left arm. We are very pleased to see her so happy and so motivated to move independently! Over the course of the week, Lily moved longer distances and more effectively using her left arm like never before. She is ready to move on her own and happy about the changes she is experiencing in her body. We are so proud of you Lily! You are amazing! |
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